Hello 👋, here are some of the projects I am working on :-)
📚 Academic Projects
REVIVE: Systems biology approach for elucidating bacterial revival after antibiotic treatment
🧰 Ongoing
This is my main PhD project in the Brochado Lab. In susceptible bacterial population, antibiotics fail to eliminate a population (less than 1%) even at clinical doses. These subpopulation can revive after treatment thus leading to relapse of infections. Here we aim to identify environmental cues that help them recover after treatment. Using advanced robotic liquid handling technologies, we hope to screen for the impact of more than 2000 compounds on revival. I am also developing lots of computational and experimental pipelines to explore and validate this. This project is fully sponsored by the Hector Fellow Academy won and supervised by Prof Ana-Rita Brochado.
CBASS Project
🧰 Completed
This is one of the projects I participated in at the Brochado Lab. The lead scientist is Susanne Brenzinger.
The main question is here is: Can a phage defence system affect antibiotic 💊 action? Well, it turns out that CBASS can boost the sensitivity of antifolat antibiotics like Trimethoprim and Sulfamethoxasole 10 times more. It also enables cell lysis in presence of the drug thus making the previously bacteriostatic antibiotic bactericidal. In this project, I conducted phylogenetic analysis, protein structure prediction with Alphafold and genomic search for co-evolution of CBASS and resistance genes for sulfa-drugs.
🎳 Outside the Lab
HackBio
🧰 Literally Forever ... 🥹
This is the startup/enterprise I am developing. We equip life scientists with tech and data skills. I started working on HackBio during the height of the COVID-19 pandemic alongside some very good friends and donors. Today, we train scientists through courses, internships and workshops. Visit HackBio
NTDs in Nigeria
🧰 Looking for collaboration ... 🤗
Neglected tropical diseases are one of the most terrible things I have seen in life. They are not just diseases, but terrible diseases, and the world has actually forgotten them, including endemic countries. Awareness is really poor, even among the educated. These days, I am always looking for data to tell NTDs stories to people. Actually the map above is real data provided by good friends from the Neglected Tropical Disease Elimination Program (NTDEP), in Nigeria. Visit the dashboard above.
Hello 👋, here are some of the projects I am working on :-)
📚 Academic Projects
REVIVE: Systems biology approach for elucidating bacterial revival after antibiotic treatment
🧰 Ongoing
This is my main PhD project in the Brochado Lab. In susceptible bacterial population, antibiotics fail to eliminate a population (less than 1%) even at clinical doses. These subpopulation can revive after treatment thus leading to relapse of infections. Here we aim to identify environmental cues that help them recover after treatment. Using advanced robotic liquid handling technologies, we hope to screen for the impact of more than 2000 compounds on revival. I am also developing lots of computational and experimental pipelines to explore and validate this. This project is fully sponsored by the Hector Fellow Academy won and supervised by Prof Ana-Rita Brochado.
CBASS Project
🧰 Completed
This is one of the projects I participated in at the Brochado Lab. The lead scientist is Susanne Brenzinger.
The main question is here is: Can a phage defence system affect antibiotic 💊 action? Well, it turns out that CBASS can boost the sensitivity of antifolat antibiotics like Trimethoprim and Sulfamethoxasole 10 times more. It also enables cell lysis in presence of the drug thus making the previously bacteriostatic antibiotic bactericidal. In this project, I conducted phylogenetic analysis, protein structure prediction with Alphafold and genomic search for co-evolution of CBASS and resistance genes for sulfa-drugs.
🎳 Outside the Lab
HackBio
🧰 Literally Forever ... 🥹
This is the startup/enterprise I am developing. We equip life scientists with tech and data skills. I started working on HackBio during the height of the COVID-19 pandemic alongside some very good friends and donors. Today, we train scientists through courses, internships and workshops. Visit HackBio
NTDs in Nigeria
🧰 Looking for collaboration ... 🤗
Neglected tropical diseases are one of the most terrible things I have seen in life. They are not just diseases, but terrible diseases, and the world has actually forgotten them, including endemic countries. Awareness is really poor, even among the educated. These days, I am always looking for data to tell NTDs stories to people. Actually the map above is real data provided by good friends from the Neglected Tropical Disease Elimination Program (NTDEP), in Nigeria. Visit the dashboard above.